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Best Books and Study Material for GATE 2018 BT (Biotechnology) Paper

Biotechnology is the most trending field for research in this era. The applications of Biotechnology in health care, and industry is vast and critical. At this juncture, the GATE preparation for BT paper demands that students refer to the best GATE books for Biotechnology (BT). Given here is the list of books required for all topics covered in GATE syllabus.

GATE Books for Biotechnology (BT)

Complete List of Important Books for GATE 2018 BT – GATE Study Material for Biotechnology.

Topic Sub Topics Book
ENGINEERING MATHEMATICS
LINEAR ALGEBRA Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors Advanced Engineering Mathematics  by Erwin Kreyszig
CALCULUS Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier Series. Intermediate Mathematics by B.V.Sastry and K.Venkateswarlu
DIFFERENTIAL EQUATIONS Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE- Laplace, heat and wave equations.
PROBABILITY AND STATISTICS Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis. Introductory methods of numerical analysis by SS SASTRY.
NUMERICAL METHODS Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations. Higher Engineering Mathematics By B.S Grewal
BIOTECHNOLOGY
MICROBIOLOGY Prokaryotic and eukaryotic cell structure; Microbial nutrition, growth and control; Microbial metabolism (aerobic and anaerobic respiration, photosynthesis); Nitrogen fixation; Chemical basis of mutations and mutagens; Microbial genetics (plasmids, transformation, transduction, conjugation); Microbial diversity and characteristic features; Viruses. Microboiology by Lansing M. prescott
BIOCHEMISTRY Biomolecules and their conformation; Weak inter-molecular interactions in biomacromolecules; Chemical and functional nature of enzymes; Kinetics of single substrate and bi-substrate enzyme catalyzed reactions; Bioenergetics; Metabolism (Glycolysis, TCA and Oxidative phosphorylation); Membrane transport and pumps; Cell cycle and cell growth control; Cell signaling and signal transduction. Biochemistry by Lehninger.
MOLECULAR BIOLOGY AND GENETICS Molecular structure of genes and chromosomes; DNA replication and control; Transcription and its control; Translational processes; Regulatory controls in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extrachromosomal inheritance; Chromosomal variation; Population genetics; Transposable elements, Molecular basis of genetic diseases and applications. Principles Of Genetics 8th Edition by Eldon John Gardner, Michael J. Simmons, Peter Snustad
PROCESS BIOTECHNOLOGY Bioprocess technology for the production of cell biomass and primary/secondary metabolites, such as baker’s yeast, ethanol, citric acid, amino acids, exo- polysacharides, antibiotics and pigments etc.; Microbial production, purification and bioprocess application(s) of industrial enzymes; Production and purification of recombinant proteins on a large scale; Chromatographic and membrane based bioseparation methods; Immobilization of enzymes and cells and their application for bioconversion processes. Aerobic and anaerobic biological processes for stabilization of solid / liquid wastes; Bioremediation. Process Biotechnology Fundamentals by S. N Mukhopadhyay
BIOPROCESS ENGINEERING Kinetics of microbial growth, substrate utilization and product formation; Simple structured models; Sterilization of air and media; Batch, fed-batch and continuous processes; Aeration and agitation; Mass transfer in bioreactors; Rheology of fermentation fluids; Scale-up concepts; Design of fermentation media; Various types of microbial and enzyme reactors; Instrumentation in bioreactors. Bioprocess Engineering Principles by Pauline M. Doran
PLANT AND ANIMAL BIOTECHNOLOGY Special features and organization of plant cells; Totipotency; Regeneration of plants; Plant products of industrial importance; Biochemistry of major metabolic pathways and products; Autotrophic and heterotrophic growth; Plant growth regulators and elicitors; Cell suspension culture development: methodology, kinetics of growth and production formation, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root cultures and their cultivation. Techniques in raising transgencies. Chawla HS, Plant Biotechnology: A Practical Approach
Carl Pinkert Transgenic Animal Technology: A Laboratory Handbook.
CHARACTERISTICS OF ANIMAL CELLS Metabolism, regulation and nutritional requirements for mass cultivation of animal cell cultures; Kinetics of cell growth and product formation and effect of shear force; Product and substrate transport; Micro & macro-carrier culture; Hybridoma technology; Live stock improvement; Cloning in animals; Genetic engineering in animal cell culture; Animal cell preservation. Cell Biology: De Roberties.
IMMUNOLOGY The origin of immunology; Inherent immunity; Humoral and cell mediated immunity; Primary and secondary lymphoid organ; Antigen; B and T cells and Macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Synthesis of antibody and secretion; Molecular basis of antibody diversity; Polyclonal and monoclonal antibody; Complement; Antigen-antibody reaction; Regulation of immune response; Immune tolerance; Hyper sensitivity; Autoimmunity; Graft versus host reaction. Immunology By Kuby.
RECOMBINANT DNA TECHNOLOGY The origin of immunology; Inherent immunity; Humoral and cell mediated immunity; Primary and secondary lymphoid organ; Antigen; B and T cells and Macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Synthesis of antibody and secretion; Molecular basis of antibody diversity; Polyclonal and monoclonal antibody; Complement; Antigen-antibody reaction; Regulation of immune response; Immune tolerance; Hyper sensitivity; Autoimmunity; Graft versus host reaction. Gene cloning and DNA analysis by T.A.Brown.
BIOINFORMATICS Major bioinformatics resources (NCBI, EBI, ExPASy); Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny); Genomics and Proteomics (Large scale genome sequencing strategies; Comparative genomics; Understanding DNA microarrays and protein arrays); Molecular modeling and simulations (basic concepts including concept of force fields). Introduction to Bioinformatics 3rd edition by Arthur M. Lesk

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